Here are some related articles about immune system, thymus and Trisomy 21:
"Defective thymic protein in DS mouse model. Very good study." ~Dixie http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719062/
"Abnormal thymus in DS and auto immune response. Note, celiac disease, hypothyroidism and several other difficulties associated with DS are auto immune related. Correcting abnormal thymus may even extend to prevention of auto immune diseases." ~Dixie http://www.ncbi.nlm.nih.gov/pubmed/25556590
"The thymus is the major site of T cell production and a key organ of the immune system. Its natural involution during the course of life has cast doubts as to its importance for the integrity of our immunity in adulthood. We provide here an overview of the recent works focusing on the immunological evaluation of subjects thymectomized during early childhood due to cardiac surgery of congenital heart defects. These studies represent new advances in our appreciation of the role of the thymus in humans and more generally in our understanding of the development of immunosenescence." http://www.impactaging.com/papers/v2/n2/full/100122.html
From the abstract: "current best available evidence from nine case-control studies suggests that neonatal thymectomy affects peripheral T-cell populations both in the short- as well as long-term and results in premature immunosenescence. " http://www.ncbi.nlm.nih.gov/m/pubmed/20576655/
Heart Surgery: To Remove or Not to Remove? http://thenewleftheartkid.blogspot.com/2011/11/thymus-to-remove-or-not-to-remove-that.html
SOLUTIONS???
Supplement with Thymic Protein A
ProBoost vs ProThyma---Here is what I found: ProThyma has 1 mcg of TPA and in pill form. Proboost is 4 mcg per packet. Both are sold in a 30 day supply. Rob sent me ProBoost to try. I really like that it is already loose (no crushing pills) and it ends up being way cheaper cause one packet goes for 3 days for my daughter who is 2. I open the packet, put it on a spoon and stick it under her tongue. It must taste good because she doesn't mind one bit. http://www.amazon.com/ProBoost-Thymic.../dp/B0002HS80K
"A choline rich diet may help regenerate a thymus that is partially removed or involuted. " http://press.endocrine.org/doi/abs/10.1210/endo-30-4-574...&
"A new study that I think may be tied to problems with thymus (and related to Science Daily Article above... "Thymus Teaches Immune Cells to Ignore Vital Gut Bacteria"http://www.ncbi.nlm.nih.gov/pubmed/26283817
"Defective thymic protein in DS mouse model. Very good study." ~Dixie http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719062/
"Abnormal thymus in DS and auto immune response. Note, celiac disease, hypothyroidism and several other difficulties associated with DS are auto immune related. Correcting abnormal thymus may even extend to prevention of auto immune diseases." ~Dixie http://www.ncbi.nlm.nih.gov/pubmed/25556590
"The thymus is the major site of T cell production and a key organ of the immune system. Its natural involution during the course of life has cast doubts as to its importance for the integrity of our immunity in adulthood. We provide here an overview of the recent works focusing on the immunological evaluation of subjects thymectomized during early childhood due to cardiac surgery of congenital heart defects. These studies represent new advances in our appreciation of the role of the thymus in humans and more generally in our understanding of the development of immunosenescence." http://www.impactaging.com/papers/v2/n2/full/100122.html
From the abstract: "current best available evidence from nine case-control studies suggests that neonatal thymectomy affects peripheral T-cell populations both in the short- as well as long-term and results in premature immunosenescence. " http://www.ncbi.nlm.nih.gov/m/pubmed/20576655/
Heart Surgery: To Remove or Not to Remove? http://thenewleftheartkid.blogspot.com/2011/11/thymus-to-remove-or-not-to-remove-that.html
Defective thymic progenitor development and mature T-cell responses in a mouse model for Down syndrome
https://l.facebook.com/l.php?u=http%3A%2F%2Fwww.jimmunol.org%2Fcontent%2F193%2F5%2F2187.full&h=mAQGyM2RHSOLUTIONS???
Supplement with Thymic Protein A
ProBoost vs ProThyma---Here is what I found: ProThyma has 1 mcg of TPA and in pill form. Proboost is 4 mcg per packet. Both are sold in a 30 day supply. Rob sent me ProBoost to try. I really like that it is already loose (no crushing pills) and it ends up being way cheaper cause one packet goes for 3 days for my daughter who is 2. I open the packet, put it on a spoon and stick it under her tongue. It must taste good because she doesn't mind one bit. http://www.amazon.com/ProBoost-Thymic.../dp/B0002HS80K
"A choline rich diet may help regenerate a thymus that is partially removed or involuted. " http://press.endocrine.org/doi/abs/10.1210/endo-30-4-574...&
"A new study that I think may be tied to problems with thymus (and related to Science Daily Article above... "Thymus Teaches Immune Cells to Ignore Vital Gut Bacteria"http://www.ncbi.nlm.nih.gov/pubmed/26283817
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